St. Thomas discusses what happens if you mix consecrated wine with another liquid:

I answer that, The truth of this question is evident from what has been said already. For it was said above (3; 5, ad 2) that the species remaining in this sacrament, as they acquire the manner of being of substance in virtue of the consecration, so likewise do they obtain the mode of acting and of being acted upon, so that they can do or receive whatever their substance could do or receive, were it there present. But it is evident that if the substance of wine were there present, then some other liquid could be mingled with it.

Nevertheless there would be a different effect of such mixing both according to the form and according to the quantity of the liquid. For if sufficient liquid were mixed so as to spread itself all through the wine, then the whole would be a mixed substance. Now what is made up of things mixed is neither of them, but each passes into a third resulting from both: hence it would result that the former wine would remain no longer. But if the liquid added were of another species, for instance, if water were mixed, the species of the wine would be dissolved, and there would be a liquid of another species. But if liquid of the same species were added, of instance, wine with wine, the same species would remain, but the wine would not be the same numerically, as the diversity of the accidents shows: for instance, if one wine were white and the other red.

But if the liquid added were of such minute quantity that it could not permeate the whole, the entire wine would not be mixed, but only part of it, which would not remain the same numerically owing to the blending of extraneous matter: still it would remain the same specifically, not only if a little liquid of the same species were mixed with it, but even if it were of another species, since a drop of water blended with much wine passes into the species of wine (De Gener. i).

Now it is evident that the body and blood of Christ abide in this sacrament so long as the species remain numerically the same, as stated above (4; 76, 6, ad 3); because it is this bread and this wine which is consecrated. Hence, if the liquid of any kind whatsoever added be so much in quantity as to permeate the whole of the consecrated wine, and be mixed with it throughout, the result would be something numerically distinct, and the blood of Christ will remain there no longer. But if the quantity of the liquid added be so slight as not to permeate throughout, but to reach only a part of the species, Christ’s blood will cease to be under that part of the consecrated wine, yet will remain under the rest.

Given the doctrine of transubstantiation, at least as St. Thomas understands it, so that it implies the existence of accidents without a subject, it is very difficult to understand how such a mixing would be possible at all. But his general position here is that a process analogous to substantial change necessarily happens if you mix anything into the consecrated wine, either according to a part of the wine, or according to the whole. He explains this kind of change in article five of the same question:

I answer that, Since “the corruption of one thing is the generation of another” (De Gener. i), something must be generated necessarily from the sacramental species if they be corrupted, as stated above (Article 4); for they are not corrupted in such a way that they disappear altogether, as if reduced to nothing; on the contrary, something sensible manifestly succeeds to them.

Nevertheless, it is difficult to see how anything can be generated from them. For it is quite evident that nothing is generated out of the body and blood of Christ which are truly there, because these are incorruptible. But if the substance, or even the matter, of the bread and wine were to remain in this sacrament, then, as some have maintained, it would be easy to account for this sensible object which succeeds to them. But that supposition is false, as was stated above (75, 2,4,8).

Hence it is that others have said that the things generated have not sprung from the sacramental species, but from the surrounding atmosphere. But this can be shown in many ways to be impossible. In the first place, because when a thing is generated from another, the latter at first appears changed and corrupted; whereas no alteration or corruption appeared previously in the adjacent atmosphere; hence the worms or ashes are not generated therefrom. Secondly, because the nature of the atmosphere is not such as to permit of such things being generated by such alterations. Thirdly, because it is possible for many consecrated hosts to be burned or putrefied; nor would it be possible for an earthen body, large enough to be generated from the atmosphere, unless a great and, in fact, exceedingly sensible condensation of the atmosphere took place. Fourthly, because the same thing can happen to the solid bodies surrounding them, such as iron or stone, which remain entire after the generation of the aforesaid things. Hence this opinion cannot stand, because it is opposed to what is manifest to our senses.

And therefore others have said that the substance of the bread and wine returns during the corruption of the species, and so from the returning substance of the bread and wine, ashes or worms or something of the kind are generated. But this explanation seems an impossible one. First of all, because if the substance of the bread and wine be converted into the body and blood of Christ, as was shown above (75, 2,4), the substance of the bread and wine cannot return, except the body and blood of Christ be again changed back into the substance of bread and wine, which is impossible: thus if air be turned into fire, the air cannot return without the fire being again changed into air. But if the substance of bread or wine be annihilated, it cannot return again, because what lapses into nothing does not return numerically the same. Unless perchance it be said that the said substance returns, because God creates anew another new substance to replace the first. Secondly, this seems to be impossible, because no time can be assigned when the substance of the bread returns. For, from what was said above (4; 76, 6, ad 3), it is evident that while the species of the bread and wine remain, there remain also the body and blood of Christ, which are not present together with the substance of the bread and wine in this sacrament, according to what was stated above (Question 75, Article 2). Hence the substance of the bread and wine cannot return while the sacramental species remain; nor, again, when these species pass away; because then the substance of the bread and wine would be without their proper accidents, which is impossible. Unless perchance it be said that in the last instant of the corruption of the species there returns (not, indeed, the substance of bread and wine, because it is in that very instant that they have the being of the substance generated from the species, but) the matter of the bread and wine; which, matter, properly speaking, would be more correctly described as created anew, than as returning. And in this sense the aforesaid position might be held.

However, since it does not seem reasonable to say that anything takes place miraculously in this sacrament, except in virtue of the consecration itself, which does not imply either creation or return of matter, it seems better to say that in the actual consecration it is miraculously bestowed on the dimensive quantity of the bread and wine to be the subject of subsequent forms. Now this is proper to matter; and therefore as a consequence everything which goes with matter is bestowed on dimensive quantity; and therefore everything which could be generated from the matter of bread or wine, if it were present, can be generated from the aforesaid dimensive quantity of the bread or wine, not, indeed, by a new miracle, but by virtue of the miracle which has already taken place.

This is rather strange, because he seems to be saying that the subsequent substantial forms inhere in quantity as in a subject, and that there is no matter there. But if this is possible in any way, and in particular if things remain in this state permanently, as he seems to suggest, then there seems to be little reason not to adopt Descartes’s view of material substance in general, and say that quantity is always the subject of substantial forms, rather than saying that some parts of the world have matter as a subject, and other parts quantity. The account might be more reasonable if he were to accept that when a new substance is generated, matter again comes to be, not by being “created anew,” but because the being of matter in general is from substantial form.

As we can see, this discussion is especially complex on account of the doctrine of transubstantiation and St. Thomas’s account of that doctrine. But if we simply consider the mixing of two liquids in general, various difficulties will remain. Suppose we have a glass of water and a glass of wine, and mix the two together. What exactly will happen?

It is manifest to the senses that when we do this, there is a period of time when parts of the resulting liquid are water, just as it was, and parts are wine, just as it was, without any mixture. But what about the surface where the two are in contact? What is happening there?

According to St. Thomas, there will be a quantitative part which shares in the qualities of each. And this is pretty reasonable. Just as we can see that part is wine and part is water, at a certain point we can see that part is watery wine. But how exactly did that watery part get that way? If it is a certain size, was there a sudden transition of a part which was water into the watery wine? Or the like with the wine becoming watery? Or was there a continuous process with an expanding mixed region? The last possibility seems most consistent with what we see, but it might be difficult to analyze this in terms of substantial change, as St. Thomas does, because such a continuous process would have no first moment when the mixed substance came to be. For if it did, it would come to be with a definite size, and thus the process would not be continuous, but would imply that some part suddenly went from not being watery wine to being watery wine.

Of course, it is one thing to say there are difficulties. It is quite another to say that they mean that the thing cannot happen. So none of this proves that the mixing of liquids is not a substantial change. Nonetheless, many of the ancient naturalists were moved by such considerations to adopt some form of atomic theory. If water and wine are each composed of atoms, the mixing process is easily understood — it is simply the movement in place of these atoms. Each part of the water remains as it was even qualitatively, and likewise each part of the wine, but the resulting mixture has different sensible qualities because one cannot distinguish the diverse qualities of each, just as mixing two very fine sands of different color may appear to result in a third color, even though the grains of sand are not changing qualitatively.

Modern atomic theory, of course, has far stronger arguments for it, but they are in principle, or at least were in the 18th and 19th centuries, of a very similar kind: atomic theory simply does a good job of explaining many of the things that we see happen in the world.

This is closely related to the discussion in the last post. When we construct a bicycle out of parts, it is manifest to the senses that the parts look just like they did before they were parts. And this is necessary, if it is true that those parts are governed by the same natural laws after they become parts that they were before they became parts. For however the parts “look,” they look this way because of how they act on the senses. So if their action does not change, the “way they look” will not change. Similarly, when we mix liquids, if the water parts and the wine parts do not change how they behave, the account one gives of the mixture must be an atomic theory or something very like it. That is, there must remain very small parts that act like water, and very small parts that act like wine. Or, given that wine and water are not in fact elements, at least the basic elemental parts must continue to act like those elemental parts.